Tag Archives: arthritis pain relief

7 myths about the risks and dangers of opioid analgesics

By Maria Szalavitz for MSN Health and Fitness

Celebrity magazines all too often feature stories about overdose deaths and rehab admissions, and the Office of National Drug Control Policy is running an advertising campaign about the dangers of prescription drug abuse.

But when taken as prescribed, just how risky are drugs like OxyContin and Vicodin?

The truth might surprise you. Myths and misinformation about opioid painkillers are widespread. Here are the facts. Continue reading

Appetite Hormone May Play a Role in the Development of Osteoarthritis

New research suggests that the appetite-regulating hormone leptin may play a role in the long-recognized connection between obesity and osteoarthritis (OA). The most common form of arthritis, osteoarthritis is characterized by the breakdown and loss of cartilage and the formation of bony overgrowths in the joints.

Scientists have long known that obesity is the number one preventable risk factor for osteoarthritis, but only in recent years have they ramped up research to understand how obesity and OA are connected.

Traditionally, the connection was assumed to be related to wear and tear. More weight meant a greater load for the joints to bear. But the wear-and-tear theory did not explain why joints in the hand, which do not bear weight, are also affected by OA. To better understand the systemic role obesity might play, Farshid Guilak, Ph.D., director of orthopaedic research in the Department of Surgery at Duke University, and his colleagues studied obese mice.

In their new study, supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases and published in the journal Arthritis & Rheumatism, the group studied mice genetically engineered to lack either leptin or leptin receptors on the cells.

Leptin acts in the brain to control appetite, but to do so it must bind to receptors on cells. Removing either the molecule or the receptor has virtually the same effect — no functioning leptin. And for the mice studied, the result of no functioning leptin was a body weight approximately four times that of normal mice — which would seem like the ideal model for studying obesity-related OA. But, the mice didn’t develop OA at all. In fact, their joint cartilage was just as healthy, if not more so, than that of normal mice.

Researchers say if they can better understand the molecular mechanisms involved in OA, they may be better able to interfere with them and perhaps prevent the disease or stop its progression.

The Arthritis Foundation also provided funding for this study.

The mission of the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the U.S. Department of Health and Human Services’ National Institutes of Health, is to support research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases, the training of basic and clinical scientists to carry out this research, and the dissemination of information on research progress in these diseases. For more information about NIAMS, call the information clearinghouse at (301) 495-4484 or (877) 22-NIAMS (free call) or visit the NIAMS Web site at http://www.niams.nih.gov

Doc’s Fibromyalgia Story Part 2

This entry is part of a series, docs story»

Many things have been going on since I last updated my post. After7 months or so the Imipramine stopped working for my fibro pain. I hate when that happens, you just get use to something and bam, you have to start over.
We decided to give Cymbalta a try. The doctor more than me, I have heard many bad stories about Cymbalta, but we are all different so I went along with trying it.

At 30 mg twice a day, the pain had lessened to a 4/5 but after a few months I was starting to get a little bitchy. The doc upped it to 60 mg twice a day and the feeling bitchy went away but I was not feeling anything but my pain. I was numb, a zombie …

After fighting so hard to get the insurance to pay for the Cymbalta, I now new I would have to stop using it and try again..

In the mean time, my blood sugar levels, which had been fine for years are now running very high, My doctor has added medication, pills for now to help control the glucose levels and I cant seem to shake this extra 30 lbs I am carrying

On the Fibro front, I am now taking the newest medication, Savella 50mg twice daily, this med has been approved and used in Europe for 5 or more years, but it is new here in the States.

I must admit, the Fibro and Neuropathy pains are almost gone !!!!! My head is a lot clearer, and I feel like myself not some Zombie.. I get angry, I get happy.. this is good!

The Cymbalta required a withdrawal, that the makers do not admit to. I had to reduce the amount slowly to avoid the painful headaches and stomach aches. Then there is the brain zaps ! don’t know what else to call them, all of a sudden its like an electric shock in the brain, happens more when you twist your head or even your eyes! Well they are not as frequent now, It has been a month! that’s it for now!

Entries in this series:
  1. Docs Fibromyalgia Story
  2. Doc's Fibromyalgia Story Part 2
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Nutra Pharma Announces Launch of Cobroxin, an Over-the-Counter (OTC) Treatment for Stage 2 (Moderate to Severe) Chronic Pain

PLANTATION, Fla.–(BUSINESS WIRE)–Nutra Pharma Corp. (OTCBB: NPHC), a biotechnology company that is developing treatments for Adrenomyeloneuropathy (AMN), HIV and Multiple Sclerosis (MS), has announced today that it has launched an over-the-counter (OTC) pain reliever, Cobroxin, for the treatment of Stage 2 (moderate to severe) chronic pain.

Cobroxin is the first OTC pain reliever clinically proven to treat Stage 2 (moderate to severe) chronic pain. The drug, which was developed by Nutra Pharma’s wholly-owned drug discovery subsidiary, ReceptoPharm, will be available as an oral spray for treating lower back pain, migraines, neck aches, shoulder pain, cramps and neuralgia and as a topical gel for treating repetitive stress, arthritis, and joint pain.

Additional benefits to Cobroxin include:

* All Natural
* Non-Addictive
* Non-Narcotic
* Non-Opiate
* More Potent than Morphine
* Long Lasting

“Cobroxin is a next generation pain reliever that addresses physician and consumer demand for a safer and less costly treatment for chronic pain,” commented Rik J Deitsch, Chairman and CEO of Nutra Pharma Corporation. “Cobroxin provides affordable and accessible pain relief for those without healthcare coverage, for those looking for a safer and effective treatment for pain, and for those not receiving effective or lasting relief from OTC NSAIDs,” he added.

Pain is the single most common reason patients seek medical care and accounts for half of all physician office visits in the United States. According to the American Pain Foundation, each year, more than 25 million people in the United States experience acute pain as a result of injury or surgery. Additionally, more than 50 million people in the United States are affected by ongoing chronic pain.

Current treatments for chronic pain include both opiate-based analgesics including Vicodin, Percocet, and Morphine, and those containing acetaminophen, such as Tylenol. Debate surrounding the use of opiates primarily focuses on the negative side effects observed with opiate-based analgesics, including nausea, vomiting, drowsiness, itching, constipation, respiratory depression, addiction, severe withdrawal symptoms and the buildup of tolerance, requiring higher dosage over time to experience the same effect. Additionally, recent media coverage has highlighted the dangers of using analgesics containing acetaminophen, which, in higher dosages, can cause liver damage or even death.

“What differentiates Cobroxin from other current analgesics is that it uses a novel mechanism of action discovered from cobra venom peptides for treating pain without the negative side effects observed in current opiate-based analgesics and those containing acetaminophen,” explained Dr. Paul Reid, CEO of Nutra Pharma’s wholly-owned drug discovery subsidiary, ReceptoPharm. “With extensive supporting evidence from 46 human clinical studies and a well-defined safety profile, we believe that Cobroxin will soon become the preferred method for treating chronic pain,” he concluded.

In preparation for commercializing Cobroxin, Nutra Pharma recently announced that ReceptoPharm had filed a patent application for a novel composition and method for oral delivery of cobra venom for the treatment of pain. The company plans to begin marketing and selling Cobroxin upon successful submission of final packaging and labeling to the FDA.

About Nutra Pharma Corp.

Nutra Pharma Corp. is a biopharmaceutical company specializing in the acquisition, licensing and commercialization of pharmaceutical products and technologies for the management of neurological disorders, cancer, autoimmune and infectious diseases. Nutra Pharma Corp. through its subsidiaries carries out basic drug discovery research and clinical development and also seeks strategic licensing partnerships to reduce the risks associated with the drug development process. The Company’s subsidiary, ReceptoPharm, Inc., is developing these technologies for the production of drugs for HIV and Multiple Sclerosis (“MS”). The Company’s subsidiary, Designer Diagnostics, is engaged in the research and development of diagnostic test kits designed to be used for the rapid identification of infectious diseases such as Paratuberculosis (para-TB) and Mycobacterium avium-intracellulare (MAI). Nutra Pharma continues to identify and acquire intellectual property and companies in the biotechnology arena.

How can therapy support pain management?

by John Scott

The longer the pain lasts, the more difficult it is to treat. The research strongly suggests that a mixture of physical and psychological therapies offers the best chance for improving outcomes. One of the most common forms of pain affects the lower back. Yet it is often the case that there is no biological evidence of the cause of the pain. No apparent external injury. No x-ray or other scan image of internal injury. The most usual association is with changes in mood, variations in the levels of anxiety or stress, or social episodes which trigger the sensation of pain. In other words, the way you perceive pain cannot be divorced from you as a person and the collection of memories and experiences that define you as an individual. So if pain persists despite the standard medical treatments (including the use of drugs such as tramadol), it is time to expand the range of treatment to include therapy.

The primary problem is that people quite naturally make their own condition worse. When they feel pain, they stop moving. They generally avoid doing the things most likely to cause the pain. More often than not, this means they rest. Unfortunately, when you rest, you lose muscle tone and tend to become stiff. This actually worsens the initial condition. Because you feel you cannot continue to function, you lose self-respect. Now confining yourself to bed, you lose your role as breadwinner or homemaker. This may impose financial hardship on the family or damage your relationship. As your mood darkens, depression can further amplify the symptoms.

Physicians are trained to apply a “scientific” approach to patient care. They make a diagnosis and supply the treatment recommended. If the diagnosis is correct, the patient gets better. Psychiatrists and therapists do not deal with the world in such black-and-white terms. They take a more holistic view of the patient. If there is disability and distress, those symptoms should also be addressed. The intention is to improve the way in which anyone deals with the pain. It offers coping strategies, problem solving and giving people a way to resume activities and thus relieve frustration. The more people can be given back some control over their lives, the more likely it is that they will begin to think more positively about their situation.

It is important to begin with physical therapy to improve mobility. Therapists will analyze activities and teach people how to get the same results by modifying their behavior. Add in relaxation training and stress management exercises, and you now begin to see a more complete route to recovery. This is a team effort with psychologists working alongside occupational therapists, physicians and nurses. Thus, if a physiotherapist gains some insight into the beliefs and fears a patient has about mobility, a program of reward and reinforcement can be established which teaches people about how their body works and why their fears are exaggerated. Noone can force you into anything. But if you are shown a better way, most will take it if given the right incentives.

Not everyone does respond to therapy, resisting interference in the way “they” do things. It also relies on effective management of the team expected to deliver these results. So, it is easy for non-medical treatment to fail (which will often confirm the patient’s prejudices). But there are many who do respond well, moving away from reliance on drugs such as tramadol as they learn how to function within the limits set by their bodies (and minds). Unfortunately, this approach is expensive. A physician sees a patient for a few minutes, writes a prescription and moves on to the next patient. This is an “efficient” use of resources. The behavioral model requires more people. Conventional hospital and health service models find this an uneconomic use of scarce resources (often choosing not to research the effectiveness of this approach to treatment). Nevertheless, there is a growing and substantial body of research now attesting to the effectiveness of this form of approach. If you have chronic pain, you should consider it.

Want to read the latest news and discussions from John Scott? Visit http://www.tramadolbliss.com/blog/?p=6 to get his latest insights on many different subjects in the world.

Article Source: How can therapy support pain management?

Approved Osteoarthritis Medicine – What You Don’t Know About Prescription Drugs Will Shock You!

by Vijay K Raisinghani

Although approved osteoarthritis medicines might provide relief from pain and other symptoms, but they also pose significant health hazards by way of adverse side effects. In many cases, they also can cause a lot of life threatening diseases. Find out the expert facts and natural treatments for osteoarthritis in this article.

To cite an example, Vioxx is a Cox-2 inhibitor drug and an approved osteoarthritis medicine manufactured by Merck. It had to be recalled from the market because it caused a lot of adverse side effects such as strokes, heart attacks and blood clots in the patient’s suffering from rheumatoid arthritis. In fact, till today there are thousands of pending cases and law suits against it.

Similarly, Bextra is a drug similar to Vioxx. It was also taken off the market due to similar reasons. It had been found to cause Stevens Johnson syndrome, which is a type of skin disorder.

Similarly, NSAIDs (non-steroidal anti-inflammatory drugs) which are approved osteoarthritis medicines also carry warning label stating that “users may face an increased risk of cardiovascular side effects and gastrointestinal bleeding”.

Corticosteroids also come under “approved osteoarthritis medicines”. They provide effective short-term relief from inflammation and pain. But they are known to cause various serious side effects such as fatigue, depression, drug dependence, abdominal pain, blurred vision, increased blood sugar levels in diabetics, etc.

Narcotic pain relievers such as oxycodone, vicodin, etc. are also approved osteoarthritis medicine. You would be shocked to know that the manufacturers of oxycodone had to pay millions of dollars as damages. It was because their sales representatives had allegedly advised the doctors that the drug was less addictive in comparison to other narcotics, whereas in reality it was one of the most addictive drugs.

Narcotic pain relievers only provide temporary pain relief as they block the pain receptors of nerve cells. In fact, they don’t reduce inflammation at all. They can cause a lot of side effects such as constipation, dry mouth, drowsiness and difficulty in urinating. They also pose the risk of causing liver damage if their use is accompanied with alcohol.

Due to the risk of such side effects, more and more people are shifting towards the use of complementary and alternative medicine (CAM). Although they are not approved osteoarthritis medicine, they are frequently recommended by medical experts. They include nutritional supplements, increased physical activity and dietary changes.

Omega-3 fatty acids play a very important role in alleviating osteoarthritis symptoms. They reduce inflammation and tenderness in joints, enhance joint mobility and decrease morning stiffness in patients suffering from rheumatoid arthritis.

Fish oil supplements are one of the best sources of omega-3 fatty acids. Although they cannot be classified as osteoarthritis medication due to FTC regulations, they are widely used as long term treatment of osteoarthritis as well as due to their amazing benefits on overall health including the heart, brain, skin, digestive system, and joints.

Omega-3 fatty acids are natural blood thinners. Therefore, in case you are taking blood thinner medications such as aspirin, you should consult your doctor before you use fish oil supplements or omega-3 supplements as a treatment for osteoarthritis. This is so that you can avoid taking too many blood thinners as that could lead to serious side effects.

Green lipped mussel found in New Zealand is also an excellent source of omega-3 fatty acids. It contains outstanding anti-inflammatory properties and helps to reduce pain and joint stiffness, increase grip strength and improves joint mobility in patients suffering from osteoarthritis.

The research on the best natural alternatives for treating osteoarthritis is going on. Newly approved osteoarthritis medicine might come up in the future. In the meantime, fish oil supplementation with a combination of green lipped mussel is one of the best natural alternatives for omega-3 supplementation and long-term treatment of osteoarthritis.

Vijay K Raisinghani is a Natural Healthcare Expert and a passionate advocate of Omega 3 Fish oils for a healthy mind and body. His website http://www.your-omega3-fish-oil-guide.com provides a wealth of information on what works and what doesn’t work in Omega 3 fish oils to achieve a young, vibrant and robust health.

Article Source: Approved Osteoarthritis Medicine – What You Don’t Know About Prescription Drugs Will Shock You!

An overview of pain management

by John Scott

Talking only about pain from a benign and not a malignant source, the standard medical approach today expands beyond the use of a simple painkiller such as tramadol and includes a number of other options. The most common is the addition of an antidepressant both for musculoskeletal and neuropathic pain. In the choice of drug, the emphasis tends to be on the tricyclic antidepressants because of their sedative properties – which incidentally helps people to sleep even when the pain levels are quite high. For neuropathic pain, it may also be appropriate to add an anticonvulsant.

More generally, it is only human to be afraid that movement will cause pain. People readily accept the idea that pain is a warning signal. They fear that if they try to work through the pain, they will actually further injure themselves. In this, a combination of psychological and physical therapies can produce excellent outcomes, allowing people to learn how to manage their pain without becoming overly dependent on medications.

But it also points to another highly relevant factor. Many people dislike taking medications, particularly painkillers which do not always have the best reputation. This emphasizes the importance of physical therapy, particularly of massage and manipulation. If the pain arises from the joints or the spine, physiotherapy can significantly reduce the intensity of the pain, improve mobility and relieve stress. In this, the relationship between the patient and the physiotherapist is vital. Once trust is established, the therapist can move the patient through the flinch response to appreciate that not all movement results in pain. Since there is also a chance for people to talk through their problems, the human interaction, if properly managed, can also improve mood.

As an alternative to physiotherapy, some people have been turning to acupuncture – a proven treatment in traditional Chinese medicine for the relief of pain. Western trained physicians are sceptical and there is little research evidence to prove its safety and effectiveness. But, with the right person delivering the treatment to a patient who has faith in its effectiveness, it is reported highly effective.

Modern technology is also moving into the field and an increasing number of patients now rely on Transcutaneous Electrical Nerve Stimulation (TENS) – a modern variation on the traditional use of electricity to “cure” muscular disorders. A TENS unit is battery driven and has one or more electric signal generators. Electrodes are placed on the skin and the generators deliver bursts of stimuli across the surface of the skin. Patients are able to vary the strength of the current, the pulse rates and amplitude. They experiment to discover the settings that produce the best results for them. Because the equipment is highly portable, it can be used anywhere. This convenience factor has increased the popularity of the device.

Even though many dismiss acupuncture and the use of a machine such a TENS as producing nothing more than a placebo effect, an increasing number of people now rely on this form of treatment and sceptics should not be too quick to deny their apparent effectiveness. After all, if the “talk” of behavioral therapists can produce measurable improvements, why should a TCM specialist or technologist not be able to do the same thing.

With over 10 years working as a professional journalist John Scott has contributed many interesting materials to http://www.tramadolbliss.com/blog/?p=4 that many users around the globe regard as a benchmark for professional writing.

Article Source: An overview of pain management

7 Ways You Can Use Ayruvedic Medicine For Arthritis Natural Treatment

by Sandra Fierling

Ayruvedic medicine is an ancient system of natural medicine from India that has been practiced there for centuries. Dr. Deepak Chopra has helped bring this ancient healing art to the North America. Now you can have arthritis natural treatment using Ayruvedic medicine.

With regard to arthritis, most pains are caused by the aggravation of one of the three doshas, (vata) and a build up of toxins (ama).

Fasting is a great way to expel toxins and the fast should be accompanied by taking two teaspoons of lemon juice with a teaspoon of honey in a cup of warm water every day – once in the morning and again in the evening.

Here are the 7 ways:

• Reduce inflammation and pain (vata) with a body massage using sesame or mustard oil.
• A light exercise routine is recommended. Listen to your body. If exercise causes you pain after one hour then stop – even if you’re only walking.
• For skeletal pain, take orange juice, lime juice or vitamin C.
• There is an Ayruvedic herb called guggul and this can be taken with warm water twice a day after meals.

• Foods that can help:
Vegetable juices and soups, which are easily digested. Also carrot, cucumber and red beets juice. Green salad with lemon and salt. Cooked vegetables include zucchini, squash and pumpkin. Fruits include apples, oranges, grapes and papaya. Spices for cooking: cumin, coriander, fennel, turmeric, ginger and asafetida.
• Foods to avoid:
Fried food, spicy food and foods that form wind like okra, spinach, potatoes, cauliflower and broccoli. Don’t indulge in an excess of tea or coffee, alcohol, white sugar, yoghurt, chocolate and cocoa. Sweets generally should be avoided as should smoking.
• Your Daily Routine:
Don’t sleep during the day and don’t stay up late. Avoid emotions such as excess fear, anxiety, worry, grief and stress.

You should consider the wisdom of Ayruveda if you have arthritis. These steps are simple to do and could ease your arthritis pain. Arthritis natural treatment using Ayruvedic medicine is very significant. Naturally, it is important to consult your doctor before doing this.

Ayruvedic Medicine is a great Arthritis Natural Treatment to consider. Visit Sandra’s website for great free arthritis tips, discount offers and more at http://arthritisreviews.com

Article Source: 7 Ways You Can Use Ayruvedic Medicine For Arthritis Natural Treatment

Tai chi improves pain in arthritis sufferers

The results of a new analysis have provided good evidence to suggest that tai chi is beneficial for arthritis

The results of a new analysis have provided good evidence to suggest that Tai Chi is beneficial for arthritis. Specifically, it was shown to decrease pain with trends towards improving overall physical health, level of tension and satisfaction with health status.

Musculoskeletal pain, such as that experienced by people with arthritis, places a severe burden on the patient and community and is recognized as an international health priority. Exercise therapy including such as strengthening, stretching and aerobic programs, have been shown to be effective for arthritic pain. Tai Chi, is a form of exercise that is regularly practiced in China to improve overall health and well-being. It is usually preformed in a group but is also practiced individually at one’s leisure, which differs from traditional exercise therapy approaches used in the clinic.

Recently, a new study examined the effectiveness of Tai Chi in decreasing pain and disability and improving physical function and quality of life in people with chronic musculoskeletal pain. The study is published in the June issue of Arthritis Care & Research (http://www3.interscience.wiley.com/journal/77005015/home). Led by Amanda Hall of The George Institute in Sydney, Australia, researchers conducted a systematic review and meta-analysis. They analyzed seven eligible randomized controlled trials that used Tai Chi as the main intervention for patients with musculoskeletal pain. The results demonstrate that Tai Chi improves pain and disability in patients suffering arthritis.

The authors state, “The fact that Tai Chi is inexpensive, convenient, and enjoyable and conveys other psychological and social benefits supports the use this type of intervention for pain conditions such as arthritis.”

“It is of importance to note that the results reported in this systematic review are indicative of the effect of Tai Chi versus minimal intervention (usual health care or health education) or wait list control,” the authors note. Establishing the specific effects of Tai Chi would require a placebo-controlled trial, which has not yet been undertaken.


Article: “The Effectiveness of Tai Chi for Chronic Musculoskeletal Pain Conditions: A Systematic Review and Meta-Analysis,” Amanda Hall, Chris Maher, Jane Latimer, Manuela Ferreira, Arthritis Care & Research, June 2009.